产品货号：
Z11332
中文名称：
ARFGAP3抗体
英文名称：
Anti-ARFGAP3 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ARFGAP3 Antibody |
| 指标别名 | ARF GAP 3;ARFGAP1;ARFGAP3 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IF,WB |
| 基因名称 | ARFGAP3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This whole rabbit serum was prepared by repeated immunizations with a truncated recombinant sequence of ArfGAP3 fused to GST. |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | Anti-ArfGAP3 antibody was prepared from monospecific antiserum by delipidation and defibrination.Further purification was used to remove the GST tag.The antibody detects ArfGAP3 in cell lysates.A BLAST analysis was used to suggest cross-reactivity with human,monkey,and orangutan for ArfGAP3.Cross-reactivity with AfGAP3 from other sources have not been determined. |
| 浓度 | 70mg/mL by Refractometry |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | This antibody is suitable for Cancer,Immunology and Nuclear Signaling research.The ArfGAPs are a family of proteins encoded by 31 genes in humans.The function of the ArfGAPs is to regulate the small G protein Arf,a regulator of membrane traffic and actin cytoskeleton.The ArfGAPs have been found to be key regulators of cellular behaviors that involve coordinated actin and membrane remodeling,including protein secretion and migration.Several ArfGAPs are associated with cancer cell invasion and metastasis,and the Arf pathway has been found to be affected in a number of genetic diseases.Although the importance of the ArfGAPs and the Arf pathway for cellular physiology is well recognized,the molecular basis for the function of these proteins has not been established.Reagents for the studies,especially antibodies specific for particular members of the ArfGAP family that can be used for immunoblotting and immunofluorescence,are not available.ArfGAP3 is one of three ArfGAPs thought to be specifically associated with the Golgi apparatus;however,localization has only been done for ectopically expressed recombinant protein and cellular function is still not established.Indeed,there is a growing controversy about the function of ArfGAP3 together with ArfGAP1 and ArfGAP2.Antibodies suitable for immunoprecipitation,immunoblotting and immunofluorescence would be of great value in addressing the controversy and for discovering the potential role of ArfGAP3 in secretion of proteins,such as growth factors,and trafficking of other proteins to the cell surface,such as growth factor receptors and cell adhesion molecules. |
| Uniprot ID | Q9NP61 |
| 推荐稀释比 | ELISA:1:5,000 IF Microscopy:1:100 IP:User Optimized WB:1:1,000 |
相关搜索：ARFGAP3抗体，ARFGAP3多抗，Anti-ARFGAP3 Antibody